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KMID : 0378019820250070091
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New Medical Journal
1982 Volume.25 No. 7 p.91 ~ p.96
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The Effect of Lesser Curvature Myotomy on Gastric Acid Output and Motility in Dogs
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Abstract
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The vagotomy has been studied as one of the common surgical treatment of peptic ulcer after Dragstedt (1974). But there were many complications; such as gastric stasis, diarrhea & dumping syndrome (Newcombe, 1973; Holle & Hart. 1974).
Recently, the highly selective vagotomy was introduced, which was selectively resecting the vagal branches to the gastric parietal cells without injury to the antral vagal branches (Amdrup & Jensen, 1970; Johnston & Wilkinson, 1970).
The highly selective vagotomy had decreasing the above complications, but it is time consuming procedure and has risk of ischemic necrosis of lesser curvature of stomach (Taylor, 1979).
Authors performed the myotomy along the lesser curvature of stomach in 7 dogs, that were resecting the vagal branches to parietal cell and preserving the vascular supplies to the stomach.
Authors checked the basal acid output & gastric acid output following pentagastrin injection, and observed the gastric motility under fluoroscopy on before and after lesser curvature myotomy.
The results were as follows;
1. The free acidity significantly decreased after lesser curvature myotomy; 48.9% in BAO (basal acid output), 46. 5% in PPAO (peak pentapeptide acid output), 50.0% in MPAO (maximal pentapeptide acid output) (p<0. 001).
2. The total acidity significantly decreased after lesser curvature myotomy; 38.6% in BAO, 36.0% in PPAO, 32.000 in MPAO (p<0.05).
3. There were no gastric motility disturbances after lesser curvature myotomy.
4. The authors infer that the lesser curvature myotomy could be a useful alternative method for peptic ulcer surgery.
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